The collection consists of two volumes. The first notebook, "Notes of Queries to William Clark, with replies," (917.3.L58.b), contains Lewis' journal of the river trip from Pittsburgh to winter camp, August 30- December 12, 1803.

This collection contains letters (1801-1802) of Commodore Dale to William Bainbridge, Samuel Barron, William Eaton, David Humphreys, Rufus King, and to British, Algerian and Tripolitanian officials. There is also a miscellaneous collection of letters (1780-1845) of Charles Biddle, James Biddle, Mahlon Dickerson, John Paul Jones, John Y. Mason, Oliver H. Perry, Edward Preble, Benjamin Stoddert, Thomas Truxtun, and others. There is a journal by Dale on a voyage to Canton, 1787-1788.

Partly copied by Redmond Conyngham from the state records and part from and with the reports of Judge Gibson and Judge Thomas Cooper. Relates to dispute over Wyoming valley lands between Connecticut and Pennsylvania. Includes correspondence of Lord Amherst, John Armstrong, Jr., Charles Biddle, John Boyd, Zebulon Butler, Thomas Cooper, Thomas Fitch, John Franklin, James Hamilton, Joseph Hamilton, William Montgomery, John Penn, Richard Rush, Jonathan Trumbull, and Roger Wolcott.